ABC Transporters in Human Diseases
English[eng]
9783040000000
ABC transporters||drug action||regulatory extension||regulatory insertion||mechanism of action||MRP1||MRP4||breast cancer||proliferation||migration||invasion||cAMP||ABCG2||ABCB1||blood-brain barrier||PET||Alzheimer’s disease||beta-amyloid||tariquidar||erlotinib||ABCG5||ABCG8||ATP-binding cassette transporter||cholesterol||polar relay||sitosterolemia||5′ untranslated region||cis-acting elements||ABCA subfamily||bioinformatics||ABC transporter||therapy response||disease-free survival||next-generation sequencing||competitive allele-specific PCR||P-glycoprotein||amyloid-beta||neuron||SK-N-SH||gene therapy||AAV||PFIC||BSEP||ABCB11||bile salts||intrahepatic cholestasis||chaperones||PFIC2||BRIC||ATP-binding cassette transporter A1 (ABCA1)||cholesterol homeostasis||reverse cholesterol transport||HDL-C||dyslipidemia||type 2 diabetes||microparticles||ABCG2 genotype||clinico-genetic analysis||ethnic specificity||genetic variations||precision medicine||rare variant||Roma||serum uric acid||SUA-lowering therapy||urate transporter||bile secretion||ABCB4||ABCC2||ABCG5/G8||molecular partners||phytosterol||xenosterol||atherosclerosis||gall stone||ABC||transporter||ABC (ATP-binding cassette) transporters||multidrug resistance||transport||trafficking||urate||mutations||polymorphisms||ABCC6||TNAP||NT5E||Pseudoxanthoma elasticum (PXE)||cancer||membrane protein||functional divergence||calcification||pseudoxanthoma elasticum||generalized arterial calcification of infancy||pyrophosphate||therapies||ABCA7||phagocytosis||Aβ peptides||yeast||multidrug transporter||anticancer||antifungal resistance||mechanism||peroxisome||adrenoleukodystrophy||fatty acids||gout||early-onset gout||hyperuricemia||uric acid||BCRP||single nucleotide polymorphism||SNP||homology modeling||substrate-binding site||cellular ATP efflux||mutagenesis||intracellular traffic||MDR3||phosphatidylcholine||RAB GTPase||taxol||drug transport||n/a